Stem Niche Pro
Simulate stem cell behavior!
“More stem cell divisions result in more differentiated cells.” – does it??
“The probability for self-renewal of a stem cell is 50%.” – is it??
Increase your understanding of stem cells with SNP!
There are a lot of ideas on how stem cells behave. Now you can see how your ideas work out, with “Stem Niche Pro” (SNP). There is also a lot of data on stem cells. See how the results of your ideas compare with actual data.
Working with SNP will increase your understanding of stem cells
The statements above seem rather basic, no need to test it. But with SNP: “hey, what the heck, it is only PC time, let’s make some runs.” And the answers? Suppose that more stem cell divisions yield initially more differentiated cells, which crowd the stem cells out of the niche, resulting in stem cell loss, resulting in less stem cells? Or maybe still other effects – depending on niche size, values in the niche, interactions between the cells. All variables that you can test with SNP. All variables the effects of which you ca understand using SNP.
Check hypotheses – without using lab time nor animals
Often an experiment is set up to test a particular hypotheses. Often results are in line with an hypothesis, but also there are arguments for another interpretation. Running several sets of parameters in SNP can give you an idea which interpretation is more likely correct.
Set up experiments that are more efficient
You can pre-experiment several hypotheses, and see what outcome shows the greatest difference, discriminates best between various hypotheses. This will enable you to better use your research resources: your time, as well as biological resources. It only requires a PC. Or several.